|
|
|
 |
 |
 |
 |
 |
Bio-X
Graduate Student Fellowships 2004
Samuel Kim
Chemistry
Professor Zare
Although a growing body of evidence suggests that many
G protein-coupled receptors exist as dimers or higher-order
oligomers, including the beta2 adrenergic receptor,
the functional significance of oligomerization remains
to be determined. Because it is difficult to analyze
the heterogeneous populations in biological systems
by conventional techniques, single-molecule spectroscopy
is a suitable tool to study these systems. The proposed
research will use single-pair fluorescence resonance
energy transfer technique to study homodimerization
of the beta2 adrenergic receptor and will focus on its
role in receptor function. |
 |
|
 |
|
|
