Dr. Henderson is director of the Stereotactic and Functional Neurosurgery program at Stanford and thre co-director of the Stanford Neural Prosthetics Translational Laboratory (NPTL). Dr. Henderson is an expert in the surgical treatment of movement disorders and chronic pain, and is active in research to improve stereotactic navigation and the efficacy of neuromodulatory therapies for movement disorders, pain, and other neurological diseases.

His research interests encompass several areas of stereotactic and functional neurosurgery, including frameless stereotactic approaches for therapy delivery to deep brain nuclei; deformable patient-specific atlases for targeting brain structures; cortical physiology and its relationship to normal and pathological movement; neural prostheses; and the development of novel neuromodulatory techniques for the treatment of movement disorders, pain, and other neurological diseases.