Dr. Chang's basic science research interests include modulation of Transforming Growth Factor-Beta in scarless flexor tendon wound healing and tissue engineered flexor tendon grafts for hand reconstruction. He has expertise in molecular biology and tissue engineering techniques and their applications to plastic and hand surgery research. Dr. Chang is the recipient of numerous grants including two recent multi-year Federal Merit Review Awards on "Tissue Engineered Flexor Tendon Grafts for Extremity Reconstruction" and "Optimization of Bioengineered Tendons Using Bioreactors and Stem Cells".