Dr. Yang's research is focused on bridging the translational gap at the interface of molecular biology, engineering, and acute care medicine. The investigative interest of the Yang lab falls within the general theme of developing advanced molecular diagnostic technologies for acute care medicine and is divided into 2 areas:

1. integrating novel molecular, sensor, and microfluidic technologies into high-content diagnostic system for broad-range pathogen detection and characterization, and
2. discovering epigenetic and transcriptional biomarkers for improved diagnosis and prognosis of critical systemic illnesses.