Home Department: Biomechanical Engineering
Supported by: Bio-X
Mentor: Marc Levenston, Mechanical Engineering

Osteoarthritis (OA) of the knee is a debilitating disease, and degradation of the meniscus during OA compromises its ability to stabilize and distribute load at the knee. Currently, we cannot detect early changes in the meniscus that lead to OA, but Michelle’s research will use novel MRI techniques that are sensitive to meniscal changes and combine these results with biochemical and biomechanical testing of the meniscus. This could lead to methods for detecting early osteoarthritic changes non-invasively.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 24, 2017:

T2, T2*, and T1ρ Variations of Cartilage Imaged in Four ex-vivo Environments

Michelle Xiao¹, Marianne S. Black^1,2, Garry E. Gold^2,3, Brian A. Hargreaves^2,3, Marc E. Levenston^1,2,3
[Departments of Mechanical Engineering¹, Radiology², and Bioengineering³, Stanford University]