Dr. Bustamante's laboratory works on a variety of organisms and model systems ranging from humans and other primates to domesticated plant and animals. Much of their research is at the interface of computational biology, mathematical genetics, and evolutionary genomics. Examples of their research accomplishments include:
Their current research focuses on human population genomics and global health including developing statistical, computational, and genomic resources for enabling trans- and multi-ethnic genome-wide association and medical sequencing studies of complex biomedical traits.