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Giles Plant - Associate Professor of Neurosurgery

Bio-X Affiliated Faculty

Dr. Plant's laboratory’ research focuses on the repair of the injured spinal cord using adult stem cells and glial cell transplantation. They utilize animal spinal cord injury modeling (mouse and rat), neuroanatomy, immunocytochemistry, confocal microscopy, gene therapy, cell culture and molecular biology techniques in investigating the following areas:

  • Spinal cord injury: Axonal regeneration, myelination and gene therapy
  • Stem cell transplantation (adult, embryonic and iPS)
  • Endogenous stem cell activity after spinal cord injury
  • Immunomodulation therapies to potentiate cell transplantation after spinal cord injury
  • Olfactory ensheathing glia and olfactory neurogenesis
  • Peripheral nerve injury and the use of gene therapy
  • Visual system: axonal regeneration and gene therapy

Overall, the laboratory aims to develop new cellular treatments and translational protocols for human treatments, which will one day help improve the quality of life for patients with spinal cord injuries.