Home Department: Human Biology
Mentor: Gerald Crabtree, Pathology and Developmental Biology

Chromatin regulators are mutated in about 50% of all human cancers, but their modes of leading to cancer are poorly understood. Ginger will use CRISPR/Cas9 to tag chromatin regulators with a protein domain that induces the recruitment of complexes to specific genome sites. This will help elucidate the kinetics and mechanisms in which the actions of chromatin regulators can lead to mis-regulation in the state of cancer.