Dr. He's research is concentrated in the area of statistical genetics and integrative analysis of omics data, attempting to develop new statistical methodologies that aid with the identification and interpretation of complex biological pathways involved in human diseases, particularly neurological disorders.
Dr. Cheng's overall objective of his laboratory is to develop novel molecular imaging probes and techniques for non-invasive detection of cancer and its metastasis at the earliest stage, so that cancer can be cured or transformed into a chronic, manageable disease.
The research Dr. Maldonado has conducted has been focused on epidemiologic aspects of viral vaccine development and prevention of perinatal HIV transmission. A major project has been to identify the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) among children living in developing areas of the world, where OPV immunogenicity is poor. Dr. Maldonando's group has identified several factors which affect the poor immunogenicity of OPV and will conduct clinical studies to attempt to improve immunogenicity.
Dr. So is interested in the diagnosis and treatment of neuromuscular diseases, including amyotrophic lateral sclerosis, neuropathies, myasthenia gravis, and electrophysiological characterization of these disorders.