BIANXIAO CUI, DEPARTMENT OF CHEMISTRY
Attend Dr. Cui's pre-seminar presentation to learn more about Dr. Bozhi Tian's seminar, "Physical biology at the semiconductor-enabled biointerfaces", to be held Thursday, October 4th.
Imaging fluorescently-labeled DNA in live cells with nanoscale precision shows significant promise as a diagnostic tool; however, the intrinsically stochastic nature of biological systems limits our ability to interpret meaningful signals from the noise. Here we discuss the implementation of advanced, 3D microscopy into an imaging flow cytometer and the unique calibration protocol we developed, in which we rely on statistical distributions rather than the unattainable static ground-truth. We demonstrate our system on live yeast cells, attaining 3D spatial information with orders of magnitude higher throughput than previous methods.
Stanford President Marc Tessier-Lavigne and Stanford Bio-X Director Carla Shatz
Lisa Giocomo
H. Craig Heller
Dennis Wall
Rasmus Fonseca, PhD
"An integrative study of the activation mechanism of heterotrimeric protein Gs complexes"
Ninna Struck Rossen, PhD
"Engineering a tissue-mimicking platform to assess cancer metastasis therapy in vivo"
Tue Herlau, PhD
"Reliable inference of dynamical brain networks from multi-subject fMRI data"
Ravindra Majeti
Peter Santa Maria
Anson Lee
Helen Blau
Paul Wang
Eric Appel
Jonathan Pollack
Carolyn Bertozzi
Shirit Einav
Tony Wyss-Coray
Jamshid Ghajar
Thomas Südhof
Euan Ashley
Ash Alizadeh
Melanie Hayden Gephart
