Stanford Bio-X Frontiers in Interdisciplinary Biosciences Seminar
JAY HUMPHREY, YALE UNIVERSITY
The Fontan surgical procedure is used to treat children born with particular congenital heart defects, namely to provide a direct connection between the inferior vena cava and the right pulmonary artery. This procedure has proven successful in better oxygenating and delivering blood despite the absence of one ventricle. Tissue engineering promises to enable an improved vascular conduit and is in clinical trials in the USA. There is a need, however, to find an optimal scaffold design that can minimize possible post-operative complications.