May 04, 2017 12:15 PM to 1:00 PM
Clark Center Seminar Room S360
James H. Clark Center 318 Campus Drive West, Stanford, CA 94305
Event Type: 

Off the Clock: Circadian-Regulated Physiologies and Disease


Circadian regulation is composed of daily, 24-hour oscillations in biological functions and is a universal, evolutionarily conserved feature from bacteria to humans. Proper circadian regulation is fundamental to human health: chronic disruption of circadian regulation due to jetlag or night shift work is associated with multiple defects in innate immunity and metabolism. Many disease states also cause loss of circadian regulation, including neurological disorders (i.e., Alzheimer’s disease, Parkinson's disease, and autism), bacterial infection, and aging. What remains unclear is how loss of circadian regulation contributes to the progression of these diseases. Using the fruit fly as a model organism, the Shirasu-Hiza lab studies circadian-regulated physiologies in the context of disease to understand underlying pathological mechanisms and to identify new potential therapeutic targets.

May 4th, 2017 at 12:15 PM in Clark Center Seminar Room S360

Hosted by:

Aaron Straight, Associate Professor of Biochemistry; and David Schneider, Associate Professor of Microbiology & Immunology, Stanford University

Pre-Seminar May 2nd, 2017 at 12:15 PM in Clark S361