Coronavirus spike (S) glycoprotein trimers promote entry into cells and are the main targets of the humoral immune response. We demonstrated that ACE2 is a functional entry receptor for this novel coronavirus and that the receptorbinding domains of SARS-CoV-2 S and SARS-CoV S bind with similar affinities to ACE2, which correlates with the efficient spread of SARS-CoV-2 among humans.
The Extavour Lab is a collection of developmental biologists, molecular biologists, geneticists, cell biologists, zoologists, and evolutionary biologists. Their shared interest is in the evolution of the genetic mechanisms employed during early animal embryogenesis to specify cell fate, development and differentiation. They focus primarily on the evolution and development of reproductive systems, including both the germ line and the somatic components of the gonad.
This and other Stanford Bio-X seminars and events will be conducted virtually over Zoom. Please join the meeting with the information LIsted and mute your computer's audio if needed. You will need to be signed in to a Zoom account to join.
The Bonini lab specializes in using the genetically tractable model organism, Drosophila, as a tool to understand the molecular basis of disease and disorder of the brain, with a particular focus on degenerative processes including ALS/FTD, TBI and aging. They implement cutting-edge genetic, molecular and cellular approaches to develop and characterize models of these processes to study their molecular basis, with an emphasis on potential translatability to clinical improvement.
This and other Stanford Bio-X seminars and events will be conducted virtually over Zoom. Please join the meeting with the information on the webpage and mute your computer's audio if needed.