Dr. Chapman's expertise include:   Biological Imaging with Fourth-Generation Light Sources, X-ray Serial and Single Molecule Diffraction Imaging, fourier transform holography with coded apertures, ultra-high resolution optics for soft x-ray inelastic scattering, Coherent X-ray Diffractive Imaging, biological X-ray imaging, phase-contrast X-ray imaging for mesoscale characterization, adaptive Optics for EUV Lithography, and he also invented time-delay X-ray holography.