Hedgehog signaling in development, disease, and regeneration
Philip Beachy - The Ernest and Amelia Gallo Professor, Professor of Urology, of Developmental Biology and (by courtesy) of Chemical & Systems Biology
Bio-X Affiliated Faculty
Dr. Philip Beachy's lab studies the function of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation) and in injury repair and regeneration (pattern maintenance). They study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. They also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.
Research News
Stanford study provides new understanding of breast growth disorders
May 4, 2017 - Stanford Medicine Scope
Bio-X affiliates Philip Beachy and Michael Clarke have discovered a new way that the GLI2 gene impacts breast...
Diabetes impairs activity of bone stem cells in mice, inhibits fracture repair
January 11, 2017 - Stanford Medicine News Center
Bio-X affiliates Michael Longaker, Geoffrey Gurtner, Philip Beachy, Fan Yang, Stuart Goodman, and...
Hedgehog pathway plays a role in colitis, new research suggests
November 2, 2016 - Stanford Medicine Scope
Researchers under Bio-X affiliates James Chen, Maximilian Diehn, Michael Clarke, and Philip Beachy have...