CHANDRA TUCKER, UNIVERSITY OF COLORADO AT DENVER
Dr. Tucker will discuss recent work using CRY2 to regulate protein-protein interactions, alter protein localization, induce enzyme activity, or disrupt protein function using light.
JOSEPH LIAO, DEPARTMENT OF UROLOGY
Attend Dr. Liao's pre-seminar presentation to learn more about Dr. Jeff Tza-Huei Wang's seminar, "Discerning Rare Disease Biomarkers by Micro- and Nanotechnologies", to be held Thursday, March 10th.
JEFF TZA-HUEI WANG, JOHNS HOPKINS UNIVERSITY
Dr. Wang’s group has developed highly sensitive, quantitative and clinically relevant technologies for analysis of genomic markers based on the convergence of SMS, microfluidic manipulations, and quantum dots.
MICHAEL LIN, DEPARTMENTS OF NEUROBIOLOGY AND BIOENGINEERING
Attend Dr. Lin's pre-seminar presentation to learn more about Dr. David Schaffer's seminar, "Novel Technologies to Investigate the Neural Stem Cell Niche", to be held Thursday, February 11th.
Over the past decade, Dr. Schaffer's group initially developed and has been implementing directed vector evolution as a high throughput approach to engineer adeno-associated virus (AAV) variants with novel properties, including enhanced biodistribution and spread, targeted delivery to specific cells such as stem cells or their neighbors, and gene editing within a cell. This talk will discuss directed evolution of novel and biomedically relevant AAV variants, as well as the application of gene delivery technologies to investigate cells and stem cells in the nervous system.
KANG SHEN, DEPARTMENTS OF BIOLOGY AND PATHOLOGY
Attend Dr. Shen's pre-seminar presentation to learn more about his seminar, "Mechanisms of Neuronal Morphogenesis - how does a neuron take its shape?", to be held Thursday, January 14th.
Understanding the structural and dynamic information encoded in the primary sequence of a protein is one of the most fundamental challenges in modern biology. The amino acid sequence of a protein encodes more than the native three-dimensional structure; it encodes the entire energy landscape – an ensemble of conformations whose energetics and dynamics are finely tuned for folding, binding and activity. Dr. Marqusee will present her laboratory's recent results probing these sequence and environmental effects using a combination of single-molecule and ensemble-based studies.
PEHR HARBURY, DEPARTMENT OF BIOCHEMISTRY
Attend Dr. Harbury's pre-seminar presentation to learn more about Dr. Susan Marqusee's seminar, "Touring the Protein Folding Landscape: the View Depends on How and Where You Look", to be held Thursday, December 3rd.
MICHELLE MONJE, DEPARTMENT OF NEUROLOGY
Attend Dr. Monje's pre-seminar presentation to learn more about Dr. Sarah Knox's seminar, "Nerve-Stem Cell Interactions During Organ Development and Regeneration", to be held Thursday, October 29th.
Dr. Knox will describe her lab's recent findings on the mechanisms by which autonomic nerves regulate morphogenic and regenerative programs using the salivary gland as their model system.
