Membrane Transporters Beyond Crystal Structures: Dynamics and Thermodynamics of Glutamate Transporters

Frontiers in Interdisciplinary Biosciences Seminar

OLGA BOUDKER, CORNELL UNIVERSITY SCHOOL OF MEDICINE

Glutamate transporters are responsible for clearance of the neurotransmitter glutamate from the synaptic cleft following rounds of neurotransmission. They maintain steep concentration gradients of glutamate by coupling its uptake to symport of sodium ions and protons and to antiport of potassium ions. Dr. Boudker's lab has been investigating the molecular mechanism of this family of transporters.

June 04, 2015
Clark Center Seminar Room S360
James H. Clark Center 318 Campus Drive West, Stanford, CA 94305
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Molecular Structural Basis for Amyloid Formation in Alzheimer’s Disease

Frontiers in Interdisciplinary Biosciences Seminar

ROB TYCKO, NIH NIDDK

Dr. Tycko will describe the highlights of his lab’s studies of amyloid structures, beginning with investigations of β-sheet organization in fibrils formed in vitro and culminating in structural studies of fibrils derived from AD brain tissue.

May 07, 2015
Clark Center Seminar Room S360
James H. Clark Center 318 Campus Drive West, Stanford, CA 94305
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Molecular Mechanisms in the Assembly of a Presynaptic Inhibitory Microcircuit

Frontiers in Interdisciplinary Biosciences Seminar

JULIA KALTSCHMIDT, MEMORIAL SLOAN KETTERING CANCER CENTER

The regulation of information flow by local inhibitory microcircuits has a fundamental role in shaping animal behavior. In the mammalian spinal cord GABAergic inhibitory interneurons serve key functions in sensory-motor transformation.

April 09, 2015
Clark Center Seminar Room S360
James H. Clark Center 318 Campus Drive West, Stanford, CA 94305
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Frontiers in Interdisciplinary Biosciences Seminar - Materials and Protein Engineering for Engineering Immunity and Tolerance

Frontiers in Interdisciplinary Biosciences Seminar

JEFFREY HUBBELL, UNIVERSITY OF CHICAGO

Dr. Hubbell's group is particularly interested in therapeutic vaccination in cancer, and they have determined that the tumor-draining lymph node is a particularly opportune lymphoid target for cancer vaccination.

February 26, 2015
Clark Center Seminar Room S360
James H. Clark Center 318 Campus Drive West, Stanford, CA 94305
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Regulation of the 3D Genome

Frontiers in Interdisciplinary Biosciences Seminar

BING REN, UNIVERSITY OF CALIFORNIA - SAN DIEGO SCHOOL OF MEDICINE

Dr. Ren will present recent findings related to 3D genome organization in mammalian cells, with a particular focus on how chromatin organization contribute to enhancer-mediated transcriptional regulation.

October 23, 2014
Clark Center Seminar Room S360
James H. Clark Center 318 Campus Drive West, Stanford, CA 94305
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