Dr. Leppert's research aims to improve the global quality of care for patients with urologic cancer with a particular focus on kidney cancer. His laboratory is evaluating the comparative effectiveness of various kidney cancer surgeries and their impact on chronic kidney disease and its downstream effects. They are investigating nano-proteomic and novel assays to diagnose kidney cancer and predict response to therapy. They are applying epidemiology, bioinformatics, and health services methods to urologic conditions.