Awarded in 2015
Home Department: Stem Cell Biology & Regenerative Medicine
Faculty Advisors: Paul Khavari (Dermatology) and Anshul Kundaje (Genetics, Computer Science)
Research Title: Epigenomic dynamics in epithelial cancer and stem cell differentiation
Research Description: Cancer arises from the misregulation of complex molecular controls in normal cells. While progress has been made in describing events which occur when normal cells are transformed into cancer cells, we still have a very limited understanding of the broad mechanisms that allow a normal cell to lose its identity. Adam will use novel technologies to characterize hundreds of thousands of molecular features of human skin tumors. The large amount of information will require implementation of computational techniques for large datasets and will reveal new genes controlling cancer cells.
Adam is a postdoc at the Broad Institute in the labs of Dr. Aviv Regev and Dr. Alex Shalek.