Home Department: Biology
Supported by: VPUE/UAR
Mentor: Daniel Jarosz, Chemical & Systems Biology and Developmental Biology

Fungal infections that do not respond to treatment are a growing medical problem. To address this issue Alex is studying how fungi acquire drug resistance. In particular, he is exploring how the activity of the chaperone Hsp90 affects the mechanism by which cells develop resistance to the common antifungal fluconazole.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 26, 2015:

Hsp90 and the Evolution of New Traits

Alex Yuan¹, Daniel Jarosz^2,3
[Departments of Biology¹, Chemical & Systems Biology², and Developmental Biology³, Stanford University]