2015 Undergraduate Summer Research Program Participant

Home Department: Biology
Supported by: Dean of Research
Mentor: Michelle Monje, Neurology

Alfonso Ocampo is investigating the effects of chemotherapy on myelination cells in the mammalian brain. Many patients suffer from cognitive deficits, memory impairments, and delayed motor responses post chemotherapy treatment, known colloquially as "chemobrain". To better understand why some of these effects emerge, he will use a chemotherapy mouse model to better understand the effects of chemotherapy on myelinating cell populations in the brain.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 26, 2015:

Cell Intrinsic and Microenvironmental Etiologies of Chemotherapy-Induced White Matter Damage

Alfonso Ocampo1,2,3,4,6, Erin M. Gibson1,2,3,6, Lauren S. Wood1,2,3,4, James Lennon1,2,3,4, Surya Nagaraja1,2,3,4,5, Pam J. Woo1,2,3,4, Hannes Vogel1,2,3,6, Michelle Monje1,2,3,4,6
[Departments of Neurology1, Neurosurgery2, Pediatrics3, Neuroscience5, and Pathology6 and Institute for Stem Cell Biology & Regenerative Medicine4, Stanford University]