Home Department: Bioengineering
Mentor: KC Huang (Bioengineering and Microbiology & Immunology)

“A High-Throughput Assay to Quantify Host-Microbe Interactions and Identify the Microbe-Derived Metabolites”

Intestinal microbes affect host health through the production of a diverse milieu of metabolites. The Huang lab has developed a high-throughput assay to identify microbes which affect host health using the model organism Drosophila melanogaster. In this project, Amin will measure the lifespan of Drosophila m. fed fresh or spent cell-free bacteria media. After identifying health-promoting microbes, he aims to profile their corresponding metabolites using metabolomics. The results can inform novel therapies utilizing microbial-derived metabolites to promote host health.