Home Department: Biochemical Engineering
Supported by: Pitch Johnson
Mentor: Jennifer Cochran, Associate Professor of Bioengineering and of Chemical Engineering

Andrew Chou is originally from Taipei, Taiwan, and designed his own major in Biochemical Engineering because of interest in protein engineering and regenerative medicine. His research is currently aimed at optimizing rational mutations to create a single chain mutant of the platelet derived growth factor (PDGF). Since PDGF is heavily implicated in angiogenesis and proliferation of multiple types of solid tumors, PDGF is an attractive target for engineering novel protein based cancer therapeutics.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 25, 2010:

Engineering a stable single-chain platelet derived growth factor variant using yeast surface display

Andrew Chou, Mihalis Kariolis, and Jennifer Cochran
[Biochemical Engineering, Bioengineering; Stanford University]