Awarded in 2015
Home Department: Bioengineering
Faculty Advisors: Tony Wyss-Coray (Neurology), Carolyn Bertozzi (Chemistry), and Michelle James (Radiology, Neurology)

Research Title: Circulatory proteins permeate the brain via selective transport impaired with age

Research Description: Despite the explosion of scientific knowledge across therapeutic areas, the development of new breakthrough therapies has not kept up. Reconciling this mismatch requires new ways to drug the “undruggable” without compromising our ability to predict efficacy and toxicity. Andrew hopes to contribute to ongoing efforts in this area by engineering a new foundational technology that could serve as the backbone for multiple biologic drug candidates in areas of unmet clinical need. Specifically, he plans to engineer proof-of-concept targeted delivery platforms that could be differentiated against antibody-drug conjugates in oncology and used for the oral delivery of sensitive payloads in rare diseases.

WHERE IS HE NOW?

Andrew started his lab at University of California San Francisco as a Sandler Faculty Fellow.