Home Department: Computer Science
Supported by: Bio-X
Mentor: Philip Beachy, Developmental Biology and Biochemistry

The Sonic hedgehog (Shh) signaling protein expressed in brainstem neurons has an unexpected but critical role in maintenance and regeneration of taste receptor cells in taste buds on the tongue. Ankit’s project will explore how Shh from brain stem neurons controls taste receptor cell regeneration by using a tagged version of Shh to track its long-range movement along axons to the taste receptor cells on the tongue.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 24, 2017:

Visualizing Neuronal Release of Sonic Hedgehog in Taste Receptor Cell Regeneration

Ankit Baghel¹, Wan-Jin Lu¹, Philip Beachy^1,2,3
[Institute for Stem Cell Biology & Regenerative Medicine¹, Department of Biochemistry², and Howard Hughes Medical Institute³, Stanford University]