2019 Undergraduate Summer Research Program Participant

Home Department: Chemical Engineering
Mentor: Judith Frydman, Biology and Genetics

Huntington’s Disease is aPhoto of undergraduate student Anthony Flores in the lab, with a pipette in one hand and a petri dish in the other, looking up at the contents of the dish. chronic neurodegenerative disease with no curative treatment caused by toxic insoluble protein aggregation within the nuclei of neurons. Anthony will be optimizing reagents that prevent protein aggregation but are limited by poor stability in physiologic conditions. Improvement of the reagents’ stability and cellular uptake with these chemical and genetic modifications could mitigate toxic protein aggregation and prevent cell death in Huntington’s Disease neurons.