Bio-X SIGF Graduate Student Fellow

Awarded in 2016
Home Department: Biophysics
Faculty Advisors: Joseph Puglisi (Structural Biology) and Peter Sarnow (Microbiology & Immunology)

Research Title: Probing the dynamics of translation termination and recycling

Research Description: Proteins in all organisms are created from genes through a process called translation, carried out by a bio-machine called the ribosome. Upon completion, the protein is released from the ribosome (termination) and the ribosome disengages to find the next gene to translate (recycling). By integrating single-molecule techniques with in vivo studies, Arjun aims to elucidate the molecular mechanism of translation termination and recycling and apply this knowledge to better understand protein expression in bacterial cells. The new insights from these studies would provide new strategies to target bacterial translation in the field of antibiotics development.


Arjun is a Senior Scientist in R&D at Pacific Biosciences.