Home Department: Biology
Mentor: Ashby Morrison (Biology)

“Investigating Links Between Chromatin and Metabolic Signaling”

Changes in chromatin configuration are observed in various human diseases, including cancers. The INO80 complex is evolutionarily conserved across a wide range of species and plays a fundamental role in cellular processes. The genetic interactions between INO80 chromatin remodeling complex and elements of the mTOR signaling pathway, a key regulator of cell growth and metabolism, have been recently discovered. In this project, Cameron will investigate the interactions of INO80 chromatin remodeling complex in varied metabolic environments in the model yeast organism S. cerevisiae.