Home Department: Chemical Engineering
Supported by: Anonymous Donor
Mentor: Jennifer Cochran, Bioengineering

Camila Kofman is working to engineer enzymes that are capable of performing site-specific bioconjugation reactions, in which small molecules are bound to specific amino acid sequences. The hypothesis behind her work is that these enzymes will allow for highly selective antibody-drug conjugates that could be used to develop therapeutic approaches to target diseased cells, such as in cancer.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 26, 2015:

Targeted Delivery of siRNA Using Knottin-Protein Conjugates for Atherosclerosis and Abdominal Aortic Aneurysms

Camila R. Kofman¹, Sandra M. DePorter¹, Sungwon Lim¹, Jennifer R. Cochran¹
[Department of Bioengineering¹, Stanford University]