Home Department: Biology
Supported by: Bio-X
Mentor: Sharon Pitteri, Radiology
Christine is profiling the global omics of fat biopsy specimens from the Stanford Endocrinology Clinic in order to investigate the biomolecular changes that occur in the fat during the progression to type 2 diabetes mellitus. Specifically, she is responsible for characterizing and quantifying the glycoproteome of adipocytes by liquid- chromatography mass spectrometry to analyze changes in protein post-translational modifications induced by an experimental overfeeding model for insulin resistance in humans.
Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 27, 2014:
Integrating Glycoproteomics and RNA-seq in Profiling Adipose Tissue
Christine Yiwen Yeh1, Brian Donald Piening1, Sarah Michelle Totten3, Tracey Lynn McLaughlin4, Michael Snyder2, Sharon Pitteri3
[Departments of Biology1, Genetics2, Radiology3, and Medicine4, Stanford University]