Home Department: undeclared
Supported by: Stanford University Dean of Research Office
Mentor: Anthony Oro, Dermatology

Basal cell carcinoma (BCC) is the most common cancer and is derived from inappropriate signaling of the hedgehog pathway. The exceptionally high rate of mutation of advanced BCCs anoints them as an excellent model system to study mechanisms of drug resistance. Daniel is studying the role of atypical protein kinase C (aPKC) in altering the genetic sequence selectivity of Gli1, which mediates hedgehog target gene transcription.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 24, 2016:

Visualizing the Role of Cell Cycle in Epithelial Differentiation

Daniel Alber¹, Samantha Piekos¹, Sandra Melo¹, Jessica Torkelson¹, Lingjie Li¹, Gautam Shankar¹, Anthony Oro¹
[Department of Dermatology¹, Stanford University]