A physician scientist, Dr. Cornfield is actively engaged in clinical medicine, teaching and research. In clinical arena, Dr. Cornfield is a Pediatrician with an active practice in both Pediatric Pulmonary Medicine and Pediatric Critical Care Medicine. In the research arena, Dr. Cornfield's lab addresses several large thematic issues. The areas of concentration include: (i) regulation of pulmonary vascular tone; (ii) oxygen sensing in the lung; (iii) biological determinants of preterm labor focusing on myometrial smooth muscle cells; (iv) developmental regulation of barrier function in the lung; and (v) the role of hypoxia-inducible factor-1 in lung development. In addition, there is an active translational research component.