2017 Undergraduate Summer Research Program Participant

Home Department: Biology
Supported by: Anonymous Donor
Mentor: Euan Ashley, Medicine (Cardiovascular), Genetics, and Biomedical Data Science

A genome wide association study (GWAS) is a powerful tool to discover genetic variants responsible for a specific disease or heritable trait. For this project, a GWAS will be conducted on approximately 120,000 individuals who have undergone a submaximal exercise test to determine novel genetic loci that could be responsible for increased aerobic fitness. These loci could be utilized to prescribe exercise over medicine, create a drug that mimics the benefits of exercise, and elucidate the relationships between physical activity and other diseases.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 24, 2017:

Genetic Determinants of Physical Activity

David Amar3, Daryl Waggott3, David Hsu1,3, Anna Shcherbina2, Euan Ashley2,3
[Departments of Biology1 and Medicine (Division of Cardiovascular Medicine3) and Program in Biomedical Informatics2, Stanford University]