2018 Undergraduate Summer Research Program Participant

Home Department: Biology
Mentor: Nicolas Grillet, Otolaryngology (Head & Neck Surgery)

Photo of USRP student Ellen Ouyang in the laboratory, working with a pipette.Mutations in the gene LOXHD1 lead to hearing loss. LOXHD1 is curiously expressed in only two locations: hair cells and spermatids. Ellen’s project hopes to determine the localization of LOXHD1 in the testis and whether mutations in LOXHD1 that cause deafness also induce morphological defects in the spermatids of a mouse model.