Home Department: undeclared
Mentor: Craig Levin (Radiology - Molecular Imaging Program at Stanford)
“Biodegradable SERS (Surface-Enhanced Raman Scattering) Supraparticles for in vivo Multicolor Imaging”
Tumors display significant heterogeneity in which multiple biomarkers need to be analyzed for patient-specific decisions. Emma aims to develop an in vivo multiplexed imaging method with surface-enhanced Raman scattering (SERS) nanoparticles for continuous and noninvasive monitoring of such heterogeneous tumors. In particular, Emma is working on the designed synthesis of biodegradable and translatable SERS nanoparticle imaging agents through (1) simulating suprastructures of renally clearable nanoparticles to determine which conditions provide high sensitivity for preclinical Raman imaging and (2) synthesizing such structures through chemistry efforts.