Home Department: undeclared
Mentor: Creed Stary (Anesthesiology, Perioperative & Pain Medicine)

“MicroRNA Effect on Long Term Oxygen Consumption in Male and
Female Astrocytes”

Isabella aims to investigate the cellular mechanisms of sex differences in stroke with a focus on how a non-coding RNA may regulate mitochondrial dysfunction in sex-specific ways. The research will involve growing astrocyte cultures with varied levels of RNA in both male and female cultures. The team will then simulate stroke injury and measure the long-term oxygen consumption rates to determine mitochondrial function. The findings from this project could contribute to the development of novel stroke therapies.