2015 Undergraduate Summer Research Program Participant

Home Department: Biomedical Computation
Supported by: Dean of Research
Mentor: Maximilian Diehn, Radiation Oncology

Jason is studying the kinetics of circulating tumor DNA (ctDNA) in non-small cell lung cancer. ctDNA, which enters the bloodstream following cancer cell death, has the potential to serve as a noninvasive biomarker to detect and monitor tumors. By quantifying ctDNA's natural rate of degradation, he hypothesizes that the rate of tumor cell death caused by radio- or chemotherapy - the rate of ctDNA production - could then also be pinpointed.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 26, 2015:

Characterizing the Kinetics of Circulating Tumor DNA Degradation

Jason Wang1,2, Alex Lovejoy2,3, Jake Chabon1,2, Dave Kurtz4,5, Maximilian Diehn1,2,3
[Institute for Stem Cell Biology & Regenerative Medicine1, Stanford Cancer Institute2, Departments of Radiation Oncology3, Medicine (Division of Oncology)4, and Bioengineering5, Stanford University]