Home Department: Biomedical Computation
Supported by: Dean of Research
Mentor: Maximilian Diehn, Radiation Oncology

Jason is studying the kinetics of circulating tumor DNA (ctDNA) in non-small cell lung cancer. ctDNA, which enters the bloodstream following cancer cell death, has the potential to serve as a noninvasive biomarker to detect and monitor tumors. By quantifying ctDNA's natural rate of degradation, he hypothesizes that the rate of tumor cell death caused by radio- or chemotherapy - the rate of ctDNA production - could then also be pinpointed.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 26, 2015:

Characterizing the Kinetics of Circulating Tumor DNA Degradation

Jason Wang^1,2, Alex Lovejoy^2,3, Jake Chabon^1,2, Dave Kurtz^4,5, Maximilian Diehn^1,2,3
[Institute for Stem Cell Biology & Regenerative Medicine¹, Stanford Cancer Institute², Departments of Radiation Oncology³, Medicine (Division of Oncology)⁴, and Bioengineering⁵, Stanford University]