Bio-X SIGF Graduate Student Fellow

Awarded in 2016
Home Department: Biophysics
Faculty Advisors: Anshul Kundaje (Genetics, Computer Science) and Douglas Vollrath (Genetics)

Research Title: Functional genomic variation in the retinal pigment epithelium and its relevance to age-related macular degeneration

Research Description: Age-related macular degeneration (AMD) is the fourth most common cause of blindness and its origin is in the retinal pigment epithelium (RPE). Can we gain insight into the genetic mechanisms underlying AMD through interrogation of RPE cells? Using RPE cells from a human cohort, we will study how RPE genomics change in response to varying cell environments. Using state-of-the-art artificial intelligence, we will mine the experimental results to identify genetic mechanisms underlying RPE function and, ultimately, AMD.


Johnny is a senior manager at NVIDIA.