Clark Center Faculty, Seed Grant Committee Member, Bio-X Affiliated Faculty

The long term goal of the Frydman lab's research is to understand how proteins fold in living cells. Dr. Frydman's lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, they aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.