Headshot portrait of Lina Mohamad - Bio-X Undergraduate Fellow
2023 Undergraduate Summer Research Program Participant

Home Department: undeclared
Mentor: Ansuman Satpathy (Pathology)

“Engineering Immune Cells Towards Developing Patient Specific Cancer Treatments”

Clinical trials in immunotherapy for cancer that target the genetic editing of a subtype of white blood cells, called T cells, have produced variable results. This has been attributed to variations in specific receptors on the surface of these cells that are specific for each patient. In the Satpathy lab, Lina will learn several gene editing techniques that can introduce or remove specific immune receptors. She will develop an editing strategy enabling simultaneous testing samples from multiple human donors. She will expand on this new approach to test large, varied donor cell populations, generating functional data to tailor each technique for specific patient needs.