Headshot photo of smiling Asian male faculty member, Dr. Longzhi Tan, Assistant Professor of Neurobiology at Stanford University.
Bio-X Affiliated Faculty

Originally from Wuhan, China, Tan received his S.B. in Physics (minor: Biology) from MIT in 2012, studying evolution with Jeff Gore and Pardis Sabeti. He earned his Ph.D. in Systems Biology from Harvard in 2018, developing high-precision methods for single-cell genomics with Sunney Xie. He uncovered the 3D structure of the human genome in a single cell, revealed unique chromosome organization in the mouse eye and nose, and measured the true mutation spectrum of single neurons in the normal human brain. Dr. Tan also attended the Neurobiology course at MBL in 2014, and worked with Ibrahim Cisse at MIT in 2019. As a postdoc in Karl Deisseroth’s lab at Stanford Bioengineering (co-mentor: Howard Chang), Dr. Tan discovered major 3D genome transformation in the mouse brain after birth.

Dr. Tan is an Assistant Professor of Neurobiology at Stanford, and started his lab in December 2022. His awards include BWF CASI (2021), ISFS (2021), Berry Fellowship (2020), Science & SciLifeLab Grand Prize (2019), HHMI ISRF (2015), and IPhO Gold Medal (2008). Outside of the lab, he enjoys designing holiday cards, t-shirts, and music videos, and is a scientific illustrator.

Dr. Tan's research lab studies the single-cell 3D genome architectural basis of neurodevelopment and aging by developing the next generation of in vivo multi-omic assays and algorithms, and applying them to the human and mouse cerebellum.