Bio-X Graduate Student Fellow

Awarded in 2008
Home Department: Chemical & Systems Biology, Medicine
Faculty Advisors: Tom Wandless (Chemical & Systems Biology) and Michael Longaker (Surgery)

Research Title: Chemically regulated hematopoietic stem cell engraftment and expansion

Research Description: Mark was interested in developing chemical tools for improving bioscience research and medical therapies. Specifically, he worked on a technology to improve our ability to make genetic changes at targeted sites within our genome and a chemical technology to expand and control hematopoietic stem cells outside of living animals. These projects addressed major challenges for researchers and clinicians involved with genetic manipulation and stem cell biology. Both projects took advantage of the labs’ expertise in molecular biology and synthetic organic chemistry and interface with imaging, immunology, and regenerative medicine.


Mark is an Assistant Professor of Radiology with a secondary appointment in Biochemistry and Biophysics at the University of Pennsylvania.