2015 Undergraduate Summer Research Program Participant

Home Department: Human Biology
Supported by: Dean of Research
Mentor: Luis de Lecea, Psychiatry & Behavioral Sciences

Matias will be studying the consolidation of different types of memory during sleep and the effects of manipulations of different neurotransmitter systems on this process. He will, among other techniques, utilize optogenetics and neurosurgery with the model organism of the mouse in order to investigate the neural bases of memory consolidation.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 26, 2015:

Optogenetic Stimulation of VTA Dopamine Neurons in DAT-Cre Mice to Induce a Sleep to Wake Transition

Matias Silvestre1, Ada Eban-Rothschild1, Shibin Li1, William Giardino1, Luis de Lecea1
[Department of Psychiatry & Behavioral Sciences1, Stanford University]