Dr. Moseley's interest involve research and diagnosis of disease states using new techniques of magnetic resonance (MR) in research and clinical. Water diffusion-sensitive MR imaging of the brain and other tissues. Mapping brain water diffusion has revolutionized our knowledge of the onset and evolution of cerebral stroke, making the MR scanner a potential "operating room" of choice for early and effective treatment of stroke and vascular disease. Because these diffusion and blood flow maps can be rapidly acquired, rapid identification of tissues that are in need of thrombolytic therapy or cytotoxic protection in the first critical hours following stroke or during surgery can be made. This non-invasive mapping of water motion and diffusion represents a new field of imaging and has created a breakthrough in assessment and treatment in stroke.