Home Department: Science, Technology, & Society
Supported by: Bio-X
Mentor: Paul Bollyky, Medicine (Infectious Diseases) and Microbiology & Immunology

Chronic endobronchial infection with Pseudomonas aeruginosa (Pa) is present in the majority of patients with cystic fibrosis (CF) and is associated with decreasing lung function and increased morbidity and mortality. Through the Bio-X USRP, Michelle will help investigate the links between the levels of a virus that infects Pa and clinical outcomes in CF. The results of this work will inform potential efforts to use virus levels as predictors for pulmonary exacerbation and to guide antibiotic choices in Pa infection in high-risk patients with CF.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 24, 2017:

Antibodies Against Pf Phage Prevent Pseudomonas aeruginosa Wound Infections by Promoting Phagocytosis

Michelle Bach¹, Jolien Sweere¹, Heather Ishak¹, Gina Suh¹, Paul Bollyky¹
[Department of Medicine (Division of Infectious Diseases¹), Stanford University]