2014 Undergraduate Summer Research Program Participant

Home Department: Biology
Supported by: Dean of Research
Mentor: Sean Wu, Medicine (Cardiovascular Medicine)

Nick is using cardiac stem cells to investigate the molecular regulation of cardiac progenitor cells by the gene Yin Yang 1 (YY1) in vivo and in vitro. This research will contribute to the knowledge of cardiac lineage commitment, which is crucial for devising successful therapies in congenital heart disease and regenerative medicine.

Poster presented at the Stanford Bio-X Interdisciplinary Initiatives Symposium on August 27, 2014:

YY1 Expression is Sufficient for the Maintenance of the Cardiac Progenitor Cell State

Nick Flores1, Guang Li1, Serge Gregoire2, Sean Wu1
[Institute of Stem Cell & Regenerative Biology (Division of Cardiovascular Medicine, Cardiovascular Institute)1, Stanford University; Department of Medicine (Cardiovascular Research Center, Division of Cardiology)2, Massachusetts General Hospital]