2021 Undergraduate Summer Research Program Participant

Home Department: undeclared
Mentor: Erinn Rankin (Radiation Oncology - Radiation & Cancer Biology and Obstetrics & Gynecology - Gynecologic Oncology)

“Investigating DNA Repair Mechanisms Behind FLASH Radiation Therapy in Ovarian Cancer”

Phoebe’s project is focusing on comparing ultra-rapid (FLASH) irradiation to conventional radiation, and how FLASH selectively spares the tissue from radiation-induced toxicity. In particular, Phoebe will evaluate the effects on normal intestine and ovarian tumors in different genetic backgrounds including defects in various DNA damage repair pathways. Phoebe’s research includes training in imaging analysis, cell culture, tissue harvesting, animal studies, and immunofluorescence.