Photo of Stanford student and Stanford Bio-X Undergraduate Summer Research Program Participant Oluremi Akindele.
2020 Undergraduate Summer Research Program Participant

Home Department: Bioengineering
Mentor: Monther Abu-Remaileh, Chemical Engineering

“Defining the Molecular Basis for Common Hallmarks of Neurodegeneration in Lysosomal Storage Disorders and Age-Associated Neurodegenerative Diseases”

Lysosomal dysfunction is known to contribute to the onset of many of age-associated neurodegenerative diseases, and many lysosomal storage disorders are indicated by neurodegeneration found in these age-associated neurodegenerative diseases. The shared pathophysiologies of the two disease types lead us to investigate whether they share any common pathways. Remi will be identifying differentially expressed genes common to lysosomal storage disorders and neurodegenerative diseases using mRNA expression datasets to gain further insights into the role of lysosomal dysfunction in these diseases.