Awarded in 2009
Home Department: Chemistry
Faculty Advisor: Vijay Pande (Chemistry)
Research Description: Mounting research evidence suggests that soluble oligomers of amyloid beta (Aβ) peptide play a causal role in Alzheimers disease. This research project describes an interdisciplinary approach to provide valuable insight into the important problem of Aβ oligomerization. The Pande lab proposes to utilize advanced simulation techniques to provide structural, thermodynamic, and kinetic information on the structure and oligomerization of Aβ peptides. They shall obtain testable spectroscopic predictions by integrating their simulations with theoretical vibrational spectroscopy.
Yu-Shan is an assistant professor of chemistry at Tufts University.