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The Bogyo Lab is interested in developing and applying chemical tools to both image and dissect the functional roles of hydrolases in a number of human health conditions. They are currently using synthetic chemistry and biological display methods to build new covalent binding probes that allow enzyme activity to be selectively inhibited as well as imaged in complex biological samples including cells, tissues and whole organisms. The Bogyo lab is specifically interested in hydrolase enzymes important for cell signaling and pathogenesis in cancer and various microbes including S.
Dr. Alexandria Boehm is interested in pathogens in the environment including their sources, fate, and transport in natural and engineered systems. She is interested in understanding of how pathogens are transmitted to humans through contact with water, feces, and contaminated surfaces. Dr. Boehm's research is focused on key problems in both developed and developing countries with the overarching goal of designing and testing novel interventions and technologies for reducing the burden of disease.
